Pendulum put the 'pro' in probiotics

Doctor-formulated

Founded by PhD doctors and scientists from Johns Hopkins, Harvard, Berkeley, and Stanford

Proprietary strains

Featuring strains you can't get anywhere else, including live Akkermansia, a keystone strain that's been in 3,000+ scientific publications

Revolutionary manufacturing

Next-generation anaerobic strains are manufactured in our own strict, oxygen-free facility in the U.S.

Probiotic scientist

Clinical efficacy

Created Glucose Control, the only medical probiotic on the market clinically shown to improve A1C in type 2 diabetes

Cutting-edge research

We continue to drive microbiome research forward through our own rigorous research and partnerships in clinical trials

     Trusted by doctors and experts 

    Top doctors and health influencers are talking about Pendulum's cutting-edge science and life-changing products.

    • Kara Fitzgerald, ND, IFMCP

      Leading Functional Medicine, Epigenetics & Longevity Expert & Educator

      New Frontiers Clinic

    • Darshan Shah, MD

      Extend Podcast Host, “Longevity Doctor of the Year”

      Next Health Clinic

    • Mike Moreno, MD

      Bestselling Author & Weight Loss Expert

      17 Day Diet

    • Christopher Mason, PhD

      Professor of Genomics, Physiology, & Biophysics, Director

      Weill Cornell Medicine, WorldQuant Initiative for Quantitative Prediction

      Our first investor and continuing research partner. We are the first consumer microbiome company to co-develop a registry with the MayoClinic.

      Our team has served as board members for ADA chapters and the ADA Research Foundation. Pendulum was profiled at the annual ScientificSessions.

       People Are Loving Metabolic Daily 

         What is Akkermansia? 

        In 2004—the same year that smartphones came out—Akkermansia muciniphila was discovered. Today—similar to how Smartphones have changed how we communicate—Akkermansia has changed how we approach gut health. Akkermansia is a unique and novel probiotic strain that is naturally found in your gastrointestinal tract. It directly interacts with the gut lining and helps regulate the mucus lining of the gut, which helps maintain your gut lining.

        In healthy people, Akkermansia accounts for up to 4% of your intestinal bacteria. The most direct way to increase Akkermansia levels in your gut is by taking either Pendulum Akkermansia or Pendulum Glucose Control.

        Akkermansia is a keystone, beneficial strain. 

        How does Akkermansia support your health? 

        Your gut microbiome is an ecosystem that is home to tens of trillions of bacteria—some good and some bad.

        Healthy adult gut microbiomes are both relatively stable and diverse. While a well-balanced gut microbiome supports a healthy body, the opposite is true for a poorly balanced gut microbiome. So what does any of this have to do with Akkermansia? The lining of your intestines is made up of epithelial cells (i.e. the cells that cover the surfaces of bodily organs). These epithelial cells are covered in a slimy mucus layer that is rich in a protein called “mucin.” Akkermansia…loves this mucin!

        Akkermansia loves mucin so much, it uses it for energy. The more mucin that Akkermansia eats, the more it encourages epithelial cells to make additional mucin. This additional “mucin making” is what strengthens your intestinal wall, which is critical for your health. Benefits can include a) maintaining and repairing gut lining and b) stimulating GLP-1, a hormone produced by the gut, which helps maintain a healthy balance between insulin and glucose levels.

        So why is Akkermansia so hard to find? 

        Akkermansia is hard to find because it is an anaerobic strain that needs to be grown in an oxygen-free environment (like your gut). This makes Akkermansia unique, as most probiotics on shelves can tolerate oxygen. 

        How do we keep our Akkermansia alive? Our enteric capsule is acid-resistant, meaning it is tough enough to get through the very acidic stomach, through the small intestines, and into the large intestines where it can do its job.